Peripheral arterial disease is seen in the arteries of the arms and legs. In this disease, the arteries turn narrowed or blocked when plaque is slowly generated inside the artery walls. The plaque is made up of bad cholesterol, fat, calcium and inflammatory cells.
The basis of varicose veins and spider veins is detrimental valves in your veins that set aside blood to flow in the wrong direction, which causes strained and bulging veins. Ageing, pregnancy and weight gain can intensify vein diseases.